High Lp(a) Numbers: A Hidden Threat to Heart Health
Lipoprotein(a), or Lp(a), is a lesser known but significant risk factor for cardiovascular diseases. Elevated levels of Lp(a) can promote clotting and inflammation, leading to a higher risk of heart attack, stroke, aortic stenosis, and peripheral artery disease.
Wht is Lp(a)?
Lp(a) is a type of lipoprotein, a molecule made up of protein and fat that carries cholesterol through the bloodstream. Lp(a) stands out from other lipoproteins due to the presence of an extra protein known as apolipoprotein(a). This unique feature increases its tendency to cause blood clots and inflammation. Genetic factors mainly determine high levels of Lp(a), with lifestyle choices having little impact.
The Risks of High Lp(a) Levels
Heart Attack and Stroke:
Elevated Lp(a) levels can lead to the buildup of fatty deposits in the arteries, known as
atherosclerosis. This can limit blood flow and raise the risk of blood clots, potentially leading to heart attacks and strokes.
Aortic Stenosis: High Lp(a) levels are associated with the calcification of the aortic valve, leading to aortic stenosis. This condition constricts the aortic valve opening, making it more difficult for the heart to circulate blood throughout the body.
Peripheral Artery Disease (PAD): Lp(a) can also contribute to the development of PAD, a condition where the arteries that supply blood to the limbs become narrowed or blocked. This can be painful and cause numbness as well as an increased risk of infections in the affected limbs.
Managing High Lp(a) Levels
While lifestyle changes alone may not significantly lower Lp(a) levels, there are steps you can take to manage your overall cardiovascular risk:
Regular Screening: If you have a family history of heart disease or high Lp(a) levels, talk to your healthcare provider about getting tested.
Healthy Lifestyle: Maintain a heart-healthy lifestyle by eating a balanced diet, exercising regularly, and avoiding smoking.
Medications: In some cases, your doctor may prescribe medications to help manage your cholesterol levels and reduce your risk of cardiovascular events.
High Lp(a) levels are a significant but often overlooked risk factor for cardiovascular diseases. By understanding the impact of Lp(a) and taking proactive steps to manage your heart health, you can reduce your risk of serious conditions like heart attack, stroke, aortic stenosis, and peripheral artery disease.
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Dr. Vik Gongidi